For a number of reasons, it can be best to use one layout for printing and a similar but differently designed layout for data entry. The relative size of text would be only one of several reasons for that.
But a quick fix that you might try it to set the layout's zoom to something larger than 100 percent. Not only is there a control in the lower left corner of the window where you can do this manually and as a way to test to see how this works with your current layouts, you can set up a script to to set the zoom level when the file first opens.
Thanks for the tips - I will report back!