I should add that this is on Windows XP, using FMP 8.5V2 Adv. My experience level is low - medium.
This is something that I and many other people may be interested in as well.
I did find one company that says they support this: http://www.keylok.com/product/KEYLOK-Software-Protection-USB-Driverless.aspx?source=google&usb_kk=USB%20dongle&_kk=USB%20dongle&_kt=0ec82b85-0df4-4913-ac5b-36d7c6c2a2e2&gclid=CPbtveyEhaYCFcPt7QodEBQPow
If you look down at the bottom of this page, it says they support "Filemaker". I am trying to find an answer for this for the iPhone, iPod, iPad family of devices. As soon as Filemaker allows us to create .ipa (Apps) it would make it alot easier!
!!!!HINT, HINT, HINT!!!!!
There's a suggestion form you can use to request new features: http://www.filemaker.com/company/feature_request.html
While this doesn't help for FileMaker Go, I have read of developers who set up an installer to copy data into the windows registry and then had a way for their solution to check for that registry entry during start up. That at least prevents casual copying of your solution from one machine to another without using the installer.