Strange one - Shortcut keys turn screen upside down!
This combination is meant to Align Bottom edges.
On my PC, using Windows XP SP3 - the whole screen is turned upside down!!! Frigthening at first, but soon realised that Ctrl+Alt+Up Arrow turned the whole screen back. Try it and see. Its weird to see your staus bar at teh top of the screen and you mouse cursor working and icons all upside down.