I'm not sure if this will help, but you can adjust the cache size and how often it saves.
Under Edit go to Preferences then click the memory tab to make adjustments.
OK -- Here is what worked for me just today, and my average container # in my huge files is 150:* On the "Modify Table View," uncheck the "File|Container" box so its column does not try to show you a hundred tiny interactive documents that you can't see anyway. Before trying that method I upped the cache, and changed the thumbnails to permanent -- just not a good fix. When I got rid of the useless column then closed the program and started it back up -- worked immediately. No more "max number reached' messages. Hope this solution works for you too.
*BTW, the reason my files were so huge is because my Preview could handle them (like your Adobe Reader). It was not until I decided to convert to Adobe Acrobat Pro 10 today that my computer couldn't handle the load.