Yes it does work, but be aware there still appears to be a bug causing it to crash when scrolling scripts, although from my experience it occurs a lot less than it did with FM10a.
It will only work as a 32bit process. Filemaker is not a native 64bit application, but then neither are a lot of applications out there.
It works better then version 10 did. But I can still get FM 11 to crash occasionally by opening Data Viewer and switching to the 'Watch' tab. And then after crashing and restarting FM11, I've lost all definitions I'd previously stored to my Watch list.