Do you have any back up copies that aren't corrupted?
Can you open the file and save a clone of it?
If so check the clone with a recover to see if you can recover it.
If you can open it at all, you might try deleting major portions of copies of your data base to see if deleting a specific layout or table also deletes the corruption. This is a long shot, but might enable you salvage at least part of your file.
Can you export your tables to text files? This might enable you to at least salvage the data.
I also seem to remember that the folks at FMDiff offer a file repair service if you care to pay for it...
How to cope with file corruption
FileMaker Pro Indexes and Related Problems
As a database is developed and changed, it is key to save copies and clones for backup.
If the DB is on Mac, try Windows for recovery, and if on Win, try Mac.
There is a possiblity that the database is badly fragmented and or the hard drive has hard or soft damage. Try another computer.