I'll preface with I'm still learning the ins and outs of filemaker.
We used to be on some older versions of filemaker user and server, and have now upgraded to 11 on both server and user.
We now notice huge memory usages by filemaker that we did not notice before. We haven't changed our databases around and they are very basic with no outside file references, at the max our databases will have four tables with two relationships.
I've attached a couple screen shots of how much memory filemaker is using.