Go you can use all the themes and with Web Publishing you can only use the basic theme, therefore Go apps look more professional. Go is limited to iPad, iPhone, and iTouch. Web publishing is web browser based. Both can be accessed outside the local network. Using Go, Filemaker can have up to 9 users, Server 250 users, and Server Adv unlimited users. Web publishing , FileMaker can have 5 concurrent users and FilerMaker Server Adv can have 100 concurrent users.