The easiest method and one that enables you to use all the interface design features available is for each client to use FileMaker Pro to connect to the database. If you use custom web publishing to publish your database to the web or office intranet, your users can use their web browsers to connect, but this will require a great deal more design work to pull off.
If you use FileMaker Server Advanced, you can use an option known as Instant Web Publishing to publish the databse for web browser access, but this is not supported by FileMaker Server.
Thanks PhilModJunk for the answer.
How does a "Creating Runtime Applications" feature of FileMaker Pro Advanced work?
Can I create a Runtime Application from FileMaker Pro Advanced and let my users use and access to FileMaker Pro Server?
If it can be done, does each of my user still need to have FileMaker Pro installed on their laptop/PC?