Thank you for your post.
I don't have access to a Zebra printer, so I am unable to test.
First, have you checked with Zebra to make sure their printer driver is compatible with Windows 10 build 1511? Or, have other issues been reported?
On the FileMaker side, does this issue occur with all database files or just a specific database file. For example, create a new database file, place a text object on the layout, go to Print Setup to select the printer, and then go to Preview. If a new file works fine, return to your original file, create a new layout and see if the issue still occurs.
The screen shot shows the label extending beyond the bottom of the page. FileMaker is simply using the printer driver information when rendering the screen. What occurs if you extend the height of the Body part?