Not clear on a few points:
1. Is the button itself hidden, or does it not open its popover panel?
2. Does the act of clicking the popover button run any script, or depend upon any condition?
3. Does the layout itself have any script trigger attached, which might have the file hanging with the script in progress?
How about posting a screenshot or two—the layout in Browse and Layout modes.
Actually, the problem was actully my self, just forget to change the hide option on the popover panel. Thanks anyway