I have an annoying problem..Or rather, I did.
Every time i tried to go to EDIT LAYOUT, a pop-up box said it couldn't find a file..and that was all she wrote. The only way I could even close
the database was by force quit. I pondered what could be calling the database referenced???
I DID FIND A SOLUTION, so I thought I would share. On the Relationships chart under Manage Database were a couple three files from an "extinct" database. I deleted these tables and everything returned to normal. It's easy to forget a table like this that one might attach to deal with a specific issue.
Hopes this helps someone.