Do you have lots of storage free? I have been watching over a number of servers recently and found that low RAM or Storage resources will cause random parts of FMS to shut down (maybe overutilised CPU also?). You want 10gig or more depending on your solution free on the main drive to maintain reliability.
Just double checking, is WPE coming back on or is it just off?
There is heaps of SSD storage space > 250 GB free. RAM with 16 GB more than sufficient. One database with ~30GB.
FMS cache today increased from 2000 MB to 8000 MB. May be this helps.
FYI; WPE stays off ...
That doesn't sound like a resources issue, you have quite a server there.
Is it OSX or Windows? FYI my experience is with running on Windows Server 2012.
Just a little i5 Mac Mini Server OSX