I encountered this with some old XP systems several version of FM Runtime back. In my case, it turned out that the computers which failed were all Dell-built and had a registration system which included a driver which conflicted with that version of FM runtime engines.
If you have only 1 out of 20, collect info on the hardware, including source/manufacturer, and see if it is the only one of its kind.
If so, look into what the machine may have pre-installed that is non-standard.
If it si not unique (or if nothing surfaces based on it being unique), look ofr other stuff only it has. Sometimes it's drivers from old game installations, registration modules, and who knows.
And, of course, one hopes someone else reading your post may have run into something specific which is easier to track down than by process of elimination.
This gives me a few new leads to follow