The answer is yes you can make it work as it basically is Windows 20008 R2 with SBS integrated into it, but it is an unsupported configuration that will perform badly without a lot of "tweeking". Microsoft don't want you doing any "tweeking" and make it difficult.
If this is a production server I would be very, very wary of using this.
Note : I have read that SBS2011 is the last of the SBS line.
In general FMS does not support ANY SBS configuration. You might be able to get it to work but if you have any problems you're on your own.
As a further reference and FOR ONLY testing, I installed fms12a on my SBS2003 server to see if it would work while running exchange server etc.
The install went flawlessly and everything works, but I would NEVER use the configuration in a production system.
Why ? Because it is an unsupported use of FMS and compared to the same database hosted on Point In Space they are about the same speed LAN v's WAN.