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Sounds to me like you have a dialog open that has gone behind...
You can usually (from the layout menu which is probably also grey) choose to revert the layout and not save the changes...
Hey Lindsay, I never figured out what was happening. Since I had a recent back-up, I deleted the file and started over with the back-up. Whatever the issue was, it hasn't happened again and I'm going on the theory that it's something I did without realizing I was doing it.
Thanks for taking toime to answer,