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By outside of FM, do you mean an exported PDF or on printed copy?
Missing or corrupt fonts can always cause an issue, but that is a simple test on that layout. Duplicate the layout and select all and change the font and see if the problem goes away in Preview. If so, it is a missing or corrupted font.
Layouts can become corrupted in other ways too. Recreating the layout without copying and pasting will remove a lot of layout corruption issues even though it is a pain to do. However, since moving to .fmp12, I've run into a lot less layout corruption issues than I did in the past. Maybe this is just coincidental, but something I seem to be noticing.
"Just reading a PDF (in this case the FTS Advanced for FileMaker 13)"
Although the document is about FM I suggest this issue has nothing whatever to do with FM.
I was working on a copy of the file. When I went back to the original and did a search all if fine. I'm not sure why the copy had weird search behavior but all is well.