Probably just filtered portals to a reservations table. You can select a given date and the one row portals can update to display the status for each room in their portals.
Obviously, there's a lot of detail work that needs to be done, starting the the tables you design to manage rooms and reservations and what relationships you devise to link them.
You might want to take a look at this one:
It's a really neat example.
I also made a booking / reservation system in my filemaker database. It works a little bit the same as the Booking system in my link. You give in a start date and an end date and you get a listing of all the available items for that period (it's for equipment rental, not for hotel rooms.)
I also wanted to make a calendar type chart in the beginning, but this way is a lot easier. And makes more sense I think.