Try storing a reference to the file in your container instead of the actual file.
Instead of drag and drop, click in your container field, select insert | file..., find your file. Click the "Store only a reference" option at the bottom of the dialog and click Open.
To open the drawing in its native appliatoin, double click the container field.
Note: in networked databases, this only works if the original files are located on a drive that each user has mounted on their system.
Thanks for your speedy reply. Undoubtly, the reference would decrease the size dramatically. However, I need the chemical structure presented in these CS ChemDraw Drawings to be displayed. For reports and what not. I don't necessary have to embed this field in the database. Would working with multiple related Filemaker Files work? In MS Access there was a plugin software from Amara called DBPix that compressed the images that reduced the bloat. Do you know of anything similar to this for Filemaker?