Most Quotes need to be itemized. If yours do, I recommend adding a related LineItems table so that you can add a flexible number of such items which then are both listed on and totaled up on your Quotes layout.
Since you need to specify both the origin an destination for your freight charges, you need to select each value in a different field and then match on both fields to your Freight Charges table.
Quotes::OrginID = FreightCharges::OriginID AND
Qoutes::DestinationID = FreightCharges::DestinationID
This assumes that each individual record in FreightCharges Holds the rate for one specific paring of Origin and Destination.