Only if you have something like Parallels where you can run FileMaker Advanced on the windows platform. Each time you create a runtime system, it makes a "crippled copy" of the currently in use FileMaker Application to "bind" to your run time solution files. So you have to create run times for windows on a windows system and run times for macs on a mac system.
I keep VMFusion and Win7 on my MacBookAir to do this. I create on the Mac-side. I create the runtime on the Windows-side. Any edits I do, or enhancements, I do on the Mac-side.